Live in 06/02/2021 on Instagram with Mark Zuckerberg and Andrew Bosworth (Boz) @ Images, websites, links and videos about animal testing, DNA and human cell researches

Hand inserts a molecule into DNA concept design.

https://www.nih.gov/

https://www.alphaknockout.com/

https://www.fda.gov/ U.S. Food and Drug Administration

DNA and human cell research

´´Each year, more than 100 million animals—including mice, rats, frogs, dogs, cats, rabbits, hamsters, guinea pigs, monkeys, fish, and birds—are killed in U.S. laboratories for biology lessons, medical training, curiosity-driven experimentation, and chemical, drug, food, and cosmetics testing. Before their deaths, some are forced to inhale toxic fumes, others are immobilized in restraint devices for hours, some have holes drilled into their skulls, and others have their skin burned off or their spinal cords crushed. In addition to the torment of the actual experiments, animals in laboratories are deprived of everything that is natural and important to them—they are confined to barren cages, socially isolated, and psychologically traumatized. The thinking, feeling animals who are used in experiments are treated like nothing more than disposable laboratory equipment.´´ https://www.peta.org/issues/animals-used-for-experimentation/animals-used-experimentation-factsheets/animal-experiments-overview/

https://en.wikipedia.org/wiki/Animal_testing#:~:text=The%20earliest%20references%20to%20animal,the%20%22father%20of%20vivisection%22.

https://en.wikipedia.org/wiki/Animal_testing#:~:text=The%20earliest%20references%20to%20animal,the%20%22father%20of%20vivisection%22. ´´The earliest references to animal testing are found in the writings of the Greeks in the 2nd and 4th centuries BC. Aristotle and Erasistratus were among the first to perform experiments on living animals.[22] Galen, a 2nd-century Roman physician, dissected pigs and goats; he is known as the “father of vivisection”.[23] Avenzoar, a 12th-century Arabic physician in Moorish Spain also practiced dissection; he introduced animal testing as an experimental method of testing surgical procedures before applying them to human patients.[24][25]´´

https://www.genscript.com/

https://www.jax.org/jax-mice-and-services/find-and-order-jax-mice

https://www.sciencemag.org/news/2020/03/it-s-heartbreaking-labs-are-euthanizing-thousands-mice-response-coronavirus-pandemic

https://www.understandinganimalresearch.org.uk/animals/a-z-animals/mouse/

´´Mice are the most commonly used vertebrate animals in medical research. This trend looks likely to continue now that both mouse and human genomes have been mapped (80% of human genes are exactly the same as those found in mice, and at least a further 10% are very similar) allowing human genetic disorders and diseases to be studied with greater accuracy.´´

´´Often, the only way of determining the function of a human gene is to insert it into, or remove it from, the mouse genome. Many thousands of mouse strains now exist, some frozen as embryos. Eventually, such techniques could lead to new methods of preventing, treating or even curing genetic diseases and other diseases with a genetic component.´´

´´Around 87% of all genetically modified animals used in research in the UK are mice [UK 2019 figures].´´ https://www.understandinganimalresearch.org.uk/animals/a-z-animals/mouse/

´´More than 111 million mice and rats are used annually in U.S. biomedical research, according to a new study. That represents more than 99% of all lab animals.´´ https://www.sciencemag.org/news/2021/01/how-many-mice-and-rats-are-used-us-labs-controversial-study-says-more-100-million

https://www.reading.ac.uk/research/research-environment/animal-research.aspx

https://www.cyagen.com/us/en/service/humanized-knockin-mice.html?gclid=Cj0KCQjw–GFBhDeARIsACH_kdZ7-6N58Jl4pXEX8_NZMoTa4RENMY1WffWdpKGg9k7Gc9UmucnMTdcaAuNOEALw_wcB

https://www.cyagen.com/

Tel: 877-459-3975 or +1 408-969-0306 (Int’l) (8am-6pm Pacific Time)

Email: animal-service@cyagen.com (Animal Model Services)
animal-bank@cyagen.com (Cyagen Catalog Models)
cell-service@cyagen.com (Cell Products and Services)

https://en.wikipedia.org/wiki/Humanized_mouse

https://en.wikipedia.org/wiki/Humanized_mouse ´´Um camundongo humanizado é um camundongo que carrega genes, células, tecidos e / ou órgãos humanos em funcionamento. Camundongos humanizados são comumente usados ​​como modelos de pequenos animais em pesquisas biológicas e médicas para a terapêutica humana.´´

´´A humanized mouse is a mouse carrying functioning human genes, cells, tissues, and/or organs. Humanized mice are commonly used as small animal models in biological and medical research for human therapeutics.´´ https://en.wikipedia.org/wiki/Humanized_mouse

https://www.creative-biolabs.com/drug-discovery/therapeutics/humanized-mouse-models.htm?gclid=Cj0KCQjw–GFBhDeARIsACH_kdZAdFRE2h6OZ2dq7mcDroJ1JJZv-WK7J2lRtuSRVvMvEo5Bc3fVHr4aAjeeEALw_wcB

http://www.gempharmatech.com/en/market/mouse/39.html?gclid=Cj0KCQjw–GFBhDeARIsACH_kdbctRjY5EihlQESe0WeYToKdEuFofo610S0APG10WlG0kPX2AqaDP0aAq85EALw_wcB

https://www.kentscientific.com/

https://animalab.eu/partners/kent-scientific

https://www.fishersci.com/shop/products/mouse-surgical-kit/13005204

https://www.tigm.org/services/?gclid=Cj0KCQjw–GFBhDeARIsACH_kda2lTeIGaJO07yPD5I9vBkgGZChzRhRkWSnzDgXY8HtpLJ2hhohjRYaAiJTEALw_wcB

https://www.tigm.org/repository/ The World´s Largest Collection of C57 ES Cells and Mice

https://www.tigm.org/services/?gclid=Cj0KCQjw–GFBhDeARIsACH_kda2lTeIGaJO07yPD5I9vBkgGZChzRhRkWSnzDgXY8HtpLJ2hhohjRYaAiJTEALw_wcB

https://www.tigm.org/publications/

https://www.genome.gov/about-genomics/fact-sheets/Knockout-Mice-Fact-Sheet

One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs

Cell Research volume 27, pages933–945 (2017)Cite this article

https://www.nature.com/articles/cr201781

doi: 10.1007/s13238-012-2932-6
  • 1 State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China;
  • 2 College of Life Sciences, Graduate School of Chinese Academy of Sciences, Beijing 100049, China

http://www.protein-cell.org/en/article/doi/10.1007/s13238-012-2932-6?

https://www.eara.eu/?lang=pt European Animal Research Association

https://www.jax.org/about-us/where-we-work/china

´´In December, 2020, we announced the establishment of a joint venture company headquartered in Beijing, China. The newly constructed facility will increase accessibility and provide researchers in China with a more economical, convenient and immediate supply of JAX® Mice.´´https://www.jax.org/about-us/where-we-work/china

https://www.arca.fiocruz.br/handle/icict/42203

AlphaKnockout (Gene Targeting Expert System) is made possible by utilizing the computing power of Milkyway-2 of National Super Computer Center in Guangzhou, the super machine rated by TOP500 ranking as the top 1/top 2 world’s most powerful computer for the past 4 consecutive years @ The first ever photograph of light as both a particle and wave – March 2, 2015, Ecole Polytechnique Federale de Lausanne @ Very Important Links, Websites and Images of the World

The Mighty Mouse: The Impact of Rodents on Advances in Biomedical Research

Mo Med. 2013 May-Jun; 110(3): 207–211.PMCID: PMC3987984NIHMSID: NIHMS570066PMID: 23829104

Elizabeth C. Bryda, PhD

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987984/

https://www.thermofisher.com/br/en/home/life-science/cloning/gene-synthesis/geneart-gene-synthesis.html?ef_id=Cj0KCQjw–GFBhDeARIsACH_kdZjJmG4us6MSB7t6Fd-GD4U3pOu19FIhXOyt_9HptiCGKx9_cSBwJoaAuwKEALw_wcB:G:s&s_kwcid=AL!3652!3!430064204149!e!!g!!genscript&cid=bid_mol_gse_r01_co_cp1358_pjt0000_bid00000_0se_gaw_nt_con_con&gclid=Cj0KCQjw–GFBhDeARIsACH_kdZjJmG4us6MSB7t6Fd-GD4U3pOu19FIhXOyt_9HptiCGKx9_cSBwJoaAuwKEALw_wcB

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